Abstrait

Studies on Antimalarial Activity of Cyclic Peroxy Cetals using Newly Introduced Balaban Indices

Priyanka Mukadam and Dipika Sharma

In this paper, we have done the development of new anti-malarial compounds using graph theoretical descriptors as molecular descriptors for the series of peroxy cetals. The resulting QSAR (quantitative structure- activity relationship) helps the pharmaceutical chemistry for the manufacturing of new anti-malarial compounds. Here, we are using newly introduced F and G indices for proposing most significant QSAR model for modeling antimalarial activity of peroxy cetals. Results are discussed on the basis of statistical parameters.