Abstrait

Fabrication of Functionally Engineered Carbon Nanotube Matrix Solid Support for Peptide Synthesis

E. Sudha, C. Arunan, P. Sivaswaroop and K. P. Subhash Chandran

Solid Phase synthesis is a widely exploited area for the development of biologically important molecules. Usually polymer resins are used as solid support in which suitable linkers can be covalently attached. Herein, we report a novel carbon nano tube based three-dimensional network, which can be functionally engineered and can be utilized as more efficient solid support compared to polymer resins. The proposed matrix offer unique mechanical properties combined with chemical stability. The micro and nano sized pores imbibes even thick solvents easily and facilitate the r eactions with the matrix easily and efficiently. This technique is more clean and green.