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Evaluation of spilanthes acmella,murr. roots for anti-inflammatory activity

Pradeep Kumar, R.V.Savadi, Rajesh Yadav, Neta Yadav, Pankaj Kumar, Niranjan Kaushik

Aqueous roots extract of Spilanthes acmella,Murr. which is used traditionally in the treatment of rheumatism, gout and claimed to possess for its anti-inflammatory activity. In the present study, the concentration (500mg/ kg b.wt. P.O.) of aqueous roots extract of Spilanthes acmella, Murr. was evaluated for anti-inflammatory activity using paw edema model in adult albino rats.Aqueous roots extract showed significant activity (P<0.001) as compared to that of diclofenic sodium(150mg/kg P.O.) against carrageenan (0.1ml of 1%w/w) induced pawedema model in adult albino rats.