Abstrait

Effects of chemicals (minerals) and yeast (probiotic) on the haematobiochemical profile of rabbit

K.Shrivastava, R.R.Jha

In recent years the inorganic constituents in biological system have been receiving increasing attention. About 30 elements are recognized as essential to life[4]. Some are required in bulk, or at least in macroscopic amount, essentially in all forms of life. The important elements are H,Na, K,Mg, Ca, C, N, O, P, S and Cl. The others occur in trace quantities, although Fe, Cu and Zn are at the top end of this “trace” scale and are apparently, also essential to all, or at leastmost forms of life.One of themajor roles played bymetallic element in biochemistry is inmetaloenzymes and in the enzyme catalysis. The role of the metal atoms in enzymic catalysis is currently an active subject of research. The trace elements unquestionably play an important role in Pathology and Physiology of biological system. Therefore, the effect of probiotic bacterial culture and mineralmixture individually or in combinationwas studied in 24, apparently healthy weaned rabbits of 6 weeks of age. At 6th week of age, all the rabbits were randomly divided into five groups. Each group was having 6 rabbits. The differences among groups were non-significant. Group G1 was considered as control group maintained on basal diet without probiotic and mineral mixture. G2 and G3 groups were supplementedwith 2%and 4%mineralmixture, respectively alongwith basal diet. Group G4was supplemented with 60g probiotic along with basal diet whereas G5 group was supplemented with 60g probiotic and 2% mineral mixture along with basal diet. The present results showed that rabbits of G5 and G4 groups had significantly higher total serumprotein values compared with the other dietary treatments. Glucose level was observed to be the highest in the G5 group followed by G4 group. The total serum cholesterol level was reduced significantly in treatment groups as compared to control group suggesting that these feed supplements may reduce the cholesterol level and may be helpful in preventing atherosclerosis or other cardiac diseases. The highest level of lipid in blood of rabbit was observed in G5 group. The AST, ALT and ALP in serum of the rabbits did not differ significantly among treatment groups and control group indicating that these feed supplements have no adverse effect on liver, kidney, heart or other vital organs. Variation in the level of Sodium and Potassium in serum was non significant among treated group and control group. Theywere in their physiological level indicating that supplementation of probiotics/ yeast culture and mineral mixture did not change the ratio of these minerals in the blood. It further supported that these feed supplements have no adverse effect on kidney. A reduction in the cholesterol level despite increase in total lipid suggested that their effect on lipid metabolism might be leading to lower the blood level of unwanted saturated fatty acid while increasing the level of unsaturated essential fatty acids which can be concluded as most important positive effect of these feed supplements.