Abstrait

Determination of multi-class drugs in meat by liquid chromatography-mass spectrometry

R.V�������­ctor Hormaz�������¡bal, ��������yvin ��������stensvik

A simple liquid chromatographic-mass spectrometry (LC-MS/MS) method for the determination of different veterinary drugs, i.e. ß-lactams, quinolones, sulfonamides, tetracyclines, nitromidazoles, meloxicams and corticosteroids in meat is described. The sample was homogenized with extraction solution and centrifuged. The supernatant were left in the freezer (-20 °C) for 30 minutes and centrifuged. Thereafter 2.75 ml supernatant was evaporated to 0.4 mL. The sample was mixed, filtered, diluted and injected into the LC-MS/MS.