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CNS depressant activity of Hibiscus mutabilis Linn. (Malvaceae) bark

R.D.Bhalke, P.B.Ghogare, A.S.Girme, R.S.Jadhav, V.D.Tambe


Present study reports CNS depressant activity of petroleum ether, ethyl acetate and methanol extracts of Hibiscus mutabilis bark. Extracts were screened for CNS depressant activity by pentobarbitone-induced sleeping time and locomotor activity testing. Results indicate that petroleum ether extract showed best CNS depressant activity.


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