Abstrait

Chemical constituents of Cordia platythyrsa and evaluation of their glycation and urease inhibition activities

T.Atchade, B.Dabole, Achyut Adhikari, Ajmal Khan, J.T.Mbafor, M.Iqbal Choudhary

A newxanthone derivative, Cordixanthone (1-hydroxy-3,6-dimethoxy-7- methylxanthen-9-one) (1) and seven known compounds, were isolated from Cordia platythyrsa. This is the first time, xanthones are reported from the genus Cordia. Methyl orsellinate and lichexanthone were tested against the urease enzyme and methyl orsellinate was evaluated for in vitro antiglycation activity. Methyl orsellinate was found active for both of the test whereas lichexanthone showed no activity.